Lecture 21: Introduction to Steady State Metabolic Modeling

Lecture 21: Introduction to Steady State Metabolic Modeling

Introduction to Steady State Metabolic Modeling

This talk is the first of a series of four which will present biology from a systems standpoint. Just to put things in perspective, this lecture will focus on metabolic systems but specifically on a modeling approach termed steady-state metabolic modeling. The next lecture will expand on the latter concept and apply it to regulatory networks of gene expression. We will then go over systems mode...

6 . 047 / 6 . 878 Lecture 19 : Introduction to Steady State Metabolic

Lecture 20: Introduction to Steady State Metabolic Modeling

According to Matthews and van Holde, metabolism is the totality of all chemical reactions that occur in living matter. This includes catabolic reactions, which are reactions that lead to the breakdown of molecules into smaller components, and anabolic reactions, which are responsible for the creation of more complex molecules (e.g. proteins, lipids, carbohydrates, and nucleic acids) from smalle...

Introduction to Steady State Metabolic Modeling

To better understand a biological system, as how it is regulated and behavors, it may be necessary to reconstruct the system correctly. Metabolic Modeling allows for in-depth insight into comprehending the molecular mechanisms of organisms, on a systematic level. It will also help to build novel systems, as the aim of synthetic biology states. We are going to start today by looking at a particu...